Herbal Extract
Clove Extract
Also known as: Caryophyllus aromaticum, Syzygium aromaticum extract, Clove bud extract, Eugenol extract
Clove extract is derived from flower buds and contains eugenol as its primary active compound, with traditional uses in oral health and digestive support. Limited clinical evidence exists for efficacy in humans, though in vitro and animal studies suggest potential antimicrobial and anti-inflammatory properties.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Clove Extract product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations MicroDefense w/ Oregano | 79 B+ | $0.41 |
| 2 | Terra Origin Organic Turmeric Blend | 77 B+ | $0.67 |
| 3 | New Chapter Turmeric Force Detox Action | 73 B+ | $1.57 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Clove Extract should I take?
The typical range is 250-1000 mg daily (extract form varies by concentration). Safe for long-term use based on culinary history; clinical duration studies lacking
When should I take Clove Extract?
With meals or as directed. May be taken with food to minimize potential gastric irritation.
Which form of Clove Extract is best?
Extract powder. Other forms in the catalog: Capsule, Standardized extract.
Is Clove Extract safe?
Commonly reported: Mild gastrointestinal upset at high doses, Allergic reactions (rare), Topical irritation if applied directly.
Which Clove Extract supplement scores highest?
Pure Encapsulations MicroDefense w/ Oregano, at 79/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Oral health support
- Digestive comfort
- Antioxidant support
- Anti-inflammatory support
How it works
- Eugenol-mediated antimicrobial activity
- Free radical scavenging via polyphenol content
- Potential NF-κB pathway modulation
Dosage
- Typical range
- 250-1000 mg daily (extract form varies by concentration)
- Timing
- With meals or as directed
- With food
- May be taken with food to minimize potential gastric irritation
- Duration
- Safe for long-term use based on culinary history; clinical duration studies lacking
- Special populations
- Pregnant women should use cautiously; limited safety data in pediatric populations
Forms
- Extract powder· 70/100
- Capsule· 70/100
- Standardized extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset at high doses
- Allergic reactions (rare)
- Topical irritation if applied directly
Contraindications
- Severe bleeding disorders (eugenol may have mild antiplatelet effects)
- Pregnancy (at supplemental doses; culinary amounts generally recognized as safe)
- Allergy to Myrtaceae family plants
Products containing Clove Extract
Top-scoring supplements in our catalog that list Clove Extract on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Most evidence is from in vitro and animal studies. Limited peer-reviewed human clinical trials support traditional uses. The 10:1 extract concentration lacks specific human efficacy data; dosing based on traditional usage patterns.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
Related in Herbal Extract
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerWhere does Clove Extract fit in your stack?
Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.
Build my stack2 questions · free · no account needed to start
Also on iPhone — get the free app
Evidence-based supplement guides, no spam
We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.
Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.