Herbal Extract
Clove Extract
Also known as: Caryophyllus aromaticum, Syzygium aromaticum extract, Clove bud extract, Eugenol extract
Clove extract is derived from flower buds and contains eugenol as its primary active compound, with traditional uses in oral health and digestive support. Limited clinical evidence exists for efficacy in humans, though in vitro and animal studies suggest potential antimicrobial and anti-inflammatory properties.
Primary uses
- Oral health support
- Digestive comfort
- Antioxidant support
- Anti-inflammatory support
How it works
- Eugenol-mediated antimicrobial activity
- Free radical scavenging via polyphenol content
- Potential NF-κB pathway modulation
Dosage
- Typical range
- 250-1000 mg daily (extract form varies by concentration)
- Timing
- With meals or as directed
- With food
- May be taken with food to minimize potential gastric irritation
- Duration
- Safe for long-term use based on culinary history; clinical duration studies lacking
- Special populations
- Pregnant women should use cautiously; limited safety data in pediatric populations
Forms
- Extract powder· 70/100
- Capsule· 70/100
- Standardized extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset at high doses
- Allergic reactions (rare)
- Topical irritation if applied directly
Contraindications
- Severe bleeding disorders (eugenol may have mild antiplatelet effects)
- Pregnancy (at supplemental doses; culinary amounts generally recognized as safe)
- Allergy to Myrtaceae family plants
Evidence notes
Most evidence is from in vitro and animal studies. Limited peer-reviewed human clinical trials support traditional uses. The 10:1 extract concentration lacks specific human efficacy data; dosing based on traditional usage patterns.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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