Herbal Extract
Cranberry Extract (Vaccinium macrocarpon)
Also known as: Cranberry (50:1), Vaccinium macrocarpon, Cranberry concentrate, Proanthocyanidin extract
Cranberry extract is a concentrated form of the Vaccinium macrocarpon fruit, standardized for proanthocyanidins, compounds known for urinary tract health support and antioxidant properties. The 50:1 ratio indicates significant concentration.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Urinary tract health
- Antioxidant support
- Uropathogenic bacteria adhesion prevention
How it works
- Proanthocyanidins inhibit bacterial adhesion to urinary epithelium
- Antioxidant and anti-inflammatory effects
- May support normal urinary function
Dosage
- Typical range
- 300-500 mg daily (standardized to ≥30% proanthocyanidins)
- Timing
- Once or twice daily
- With food
- Can be taken with or without food; with food may reduce GI upset
- Duration
- Consistent daily use recommended; benefits typically observed within 1-2 weeks
- Special populations
- Safe for long-term use; pregnancy/lactation: generally recognized as safe but consult provider; those on anticoagulants should monitor intake
Forms
- Extract (concentrated)· 70/100
- Powder· 70/100
- Juice· 70/100
Safety
Common side effects
- Mild GI upset
- Stomach discomfort (in sensitive individuals)
Contraindications
- Warfarin/anticoagulant therapy (may increase bleeding risk at very high intakes)
Products containing Cranberry Extract (Vaccinium macrocarpon)
Top-scoring supplements in our catalog that list Cranberry Extract (Vaccinium macrocarpon) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Good evidence for urinary tract health, particularly in women; multiple RCTs support proanthocyanidin-rich cranberry extracts. 50:1 concentration ensures adequate proanthocyanidin content for efficacy.
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.