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Herbal Extract

Coriolus Versicolor Extract (Turkey Tail Mushroom)

Also known as: Turkey Tail Mushroom, Trametes versicolor, Polyporus versicolor, PSK

C
Evidence

Coriolus versicolor is a medicinal mushroom traditionally used in Asian medicine containing bioactive polysaccharides (PSK and PSP) with emerging research on immune modulation and gut health support. Most evidence comes from Asian studies and preliminary Western research; clinical application primarily established in oncology adjuvant contexts.

Primary uses

  • Immune support
  • Gut health and microbiome
  • General wellness

How it works

  • Polysaccharide-mediated immune activation (beta-glucans)
  • Potential prebiotic effects on beneficial gut bacteria
  • Antimicrobial and antioxidant properties

Dosage

Typical range
1,000–3,000 mg daily (often standardized to 30–50% polysaccharides)
Timing
Can be taken with meals; no strict timing requirement
With food
Taking with food may improve absorption and tolerability
Duration
Traditional use suggests ongoing supplementation; most studies range from 4–12 weeks
Special populations
Pregnant/nursing individuals should consult healthcare provider; autoimmune conditions warrant medical supervision

Forms

  • Sporocarp (fruiting body) extract· 70/100
  • Capsule· 70/100
  • Powder· 70/100

Safety

Common side effects

  • Generally well-tolerated
  • Rare: mild gastrointestinal upset, allergic reactions in sensitive individuals

Contraindications

  • Avoid or use cautiously with immunosuppressive medications
  • Caution in severe autoimmune conditions without medical oversight

Evidence notes

Good traditional use and emerging mechanistic research, but limited high-quality RCTs in Western populations for non-oncology applications. PSK and PSP are better studied in Asian clinical contexts. Immune claims are preliminary; more rigorous controlled trials needed in healthy populations.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.