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Chlorella

Also known as: Chlorella vulgaris, Chlorella pyrenoidosa, Broken cell wall chlorella, Green algae

B
Evidence

Chlorella is a nutrient-dense freshwater green algae containing protein, B vitamins, minerals, and chlorophyll. Evidence for specific health benefits remains limited, though it may support detoxification and overall nutritional intake.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

Add NOW Foods Certified Organic Chlorella to your stack — free
The highest-scored Chlorella product in our catalog (87/100). Track dose and overlaps in the app.
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Every Chlorella product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much Chlorella should I take?

The typical range is 2-10g daily. Safe long-term

When should I take Chlorella?

With meals. Yes.

Which form of Chlorella is best?

Broken cell wall tablets — Better digestibility. Other forms in the catalog: Powder, Capsules, Tablets.

Is Chlorella safe?

Commonly reported: GI upset initially, Green stools, Gas. Serious warnings: Start low - detox symptoms possible. May support liver detox

Which Chlorella supplement scores highest?

NOW Foods Certified Organic Chlorella, at 87/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Primary uses

  • Heavy metal binding
  • Detoxification
  • Nutrient-dense
  • Gut health
  • Nutrient density
  • Immune support
  • Nutritional supplementation
  • General wellness

What systematic reviews concluded

Outcomes that systematic reviews of Chlorella reached a verdict on: 9 with a benefit, 2 with no effect, 3 unclear. Each is quoted from a review and linked to it on PubMed. How these were read.

Reviews found a benefit (9)

Benefitendurance exercise performance
“significantly improved in TTE (SMD = 1.06, 95% CI: 0.16-1.96)” PMID 42075102
Every supplement reviewed for exercise performance →
Benefitmuscle damage markers
“CK concentrations were significantly reduced (SMD = -0.78, 95% CI: -1.28 to -0.28).” PMID 42075102
Every supplement reviewed for exercise recovery →
Benefitbody weight
“C. vulgaris supplementation demonstrated significant reductions in weight (Weighted Mean Difference [WMD]= -1.62, 95% Confidence Interval [CI]: -2.24, -1.00)” PMID 41652544
Every supplement reviewed for weight & body fat →
Benefitfasting blood glucose
“fasting blood sugar (FBS) (WMD= -6.25, 95% CI: -9.02, -3.47)” PMID 41652544 · 2 reviews
Every supplement reviewed for blood sugar →
Benefitc-reactive protein
“high-sensitivity C-reactive protein (hs-CRP) (WMD= -1.02, 95% CI: -1.84, -0.19)” PMID 41652544
Every supplement reviewed for inflammation →
Benefitliver enzymes
“alkaline phosphatase (ALP) (WMD= -14.84, 95% CI: -27.81, -1.87), and aspartate aminotransferase (AST) (WMD= -4.99, 95% CI: -7.26, -2.71).” PMID 41652544
Every supplement reviewed for liver health →

and 3 more.

Reviews found no effect (2)

No effecttriglycerides
“We found that Chlorella vulgaris supplementation had a beneficial effect on TC and LDL-C levels with no significant effect on TG and HDL-C levels.” PMID 35331862
Every supplement reviewed for cholesterol & triglycerides →
No effectbody mass index
“the changes in TG, HDL-C, and BMI were not satisfactory.” PMID 29037431
Every supplement reviewed for weight & body fat →

Not enough to say: gut microbiota composition; ldl cholesterol; anthropometric indices.

How it works

  • High chlorophyll content
  • Binds heavy metals
  • Complete protein
  • Growth factor (CGF)

Dosage

Typical range
2-10g daily
Timing
With meals
With food
Yes
Duration
Safe long-term
Special populations
Detox support, nutrient density

Forms

  • Broken cell wall tablets
  • Powder
  • Capsules

Safety

Common side effects

  • GI upset initially
  • Green stools
  • Gas

Contraindications

  • Iodine sensitivity
  • Autoimmune conditions (immune stimulating)

Products containing Chlorella

Top-scoring supplements in our catalog that list Chlorella on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

See all products →

Evidence notes

Traditional use with research on detox and nutrient content

Grade B: Some human trials support key claims; further confirmation needed.

Chlorella compared head-to-head

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.