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Herbal Extract

Chaste Berry Extract

Also known as: Vitex agnus castus, Vitex, chasteberry, monk's pepper

B
Evidence

Chaste berry (Vitex agnus castus) is a traditional herbal extract from the fruit used to support hormonal balance and menstrual cycle regulation in women. Clinical evidence supports benefit for premenstrual symptoms (PMS) and breast tenderness.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Premenstrual syndrome (PMS) support
  • Menstrual cycle regulation
  • Breast tenderness/mastalgia support
  • Hormonal balance support

How it works

  • Dopamine agonist activity
  • Pituitary hormone modulation (LH/FSH)
  • Progesterone support
  • Prolactin regulation

Dosage

Typical range
20-40 mg daily (standardized extract) or 400-500 mg fruit powder daily
Timing
Typically once daily in the morning; consistent daily use is key
With food
Can be taken with or without food; morning dosing preferred
Duration
Effects typically observed after 3-6 cycles of menstruation; requires consistent use over weeks/months
Special populations
Avoid in pregnancy; controversial in nursing; avoid with estrogen-dependent conditions

Forms

  • Extract (standardized)· 70/100
  • Fruit powder· 70/100
  • Liquid extract· 70/100
  • Standardized extract (agnusides)· 70/100

Safety

Common side effects

  • Mild gastrointestinal upset
  • Headache (rare)
  • Nausea (rare)
  • Rash/skin reactions (rare)

Contraindications

  • Pregnancy (potential uterotonic effects)
  • Nursing (effects on milk supply unclear; use cautiously)
  • Estrogen-dependent cancers (theoretical concern)
  • Pituitary tumors or disorders

Evidence notes

Multiple RCTs demonstrate efficacy for PMS symptoms, particularly breast pain and mood changes. Evidence is good for short-term use (3-6 months); long-term safety data is more limited. Considered one of the better-evidenced herbal options for women's hormonal support.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.