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Herbal Extract

Chaste Berry Extract

Also known as: Vitex agnus castus, Vitex, chasteberry, monk's pepper

B
Evidence

Chaste berry (Vitex agnus castus) is a traditional herbal extract from the fruit used to support hormonal balance and menstrual cycle regulation in women. Clinical evidence supports benefit for premenstrual symptoms (PMS) and breast tenderness.

Primary uses

  • Premenstrual syndrome (PMS) support
  • Menstrual cycle regulation
  • Breast tenderness/mastalgia support
  • Hormonal balance support

How it works

  • Dopamine agonist activity
  • Pituitary hormone modulation (LH/FSH)
  • Progesterone support
  • Prolactin regulation

Dosage

Typical range
20-40 mg daily (standardized extract) or 400-500 mg fruit powder daily
Timing
Typically once daily in the morning; consistent daily use is key
With food
Can be taken with or without food; morning dosing preferred
Duration
Effects typically observed after 3-6 cycles of menstruation; requires consistent use over weeks/months
Special populations
Avoid in pregnancy; controversial in nursing; avoid with estrogen-dependent conditions

Forms

  • Extract (standardized)· 70/100
  • Fruit powder· 70/100
  • Liquid extract· 70/100
  • Standardized extract (agnusides)· 70/100

Safety

Common side effects

  • Mild gastrointestinal upset
  • Headache (rare)
  • Nausea (rare)
  • Rash/skin reactions (rare)

Contraindications

  • Pregnancy (potential uterotonic effects)
  • Nursing (effects on milk supply unclear; use cautiously)
  • Estrogen-dependent cancers (theoretical concern)
  • Pituitary tumors or disorders

Evidence notes

Multiple RCTs demonstrate efficacy for PMS symptoms, particularly breast pain and mood changes. Evidence is good for short-term use (3-6 months); long-term safety data is more limited. Considered one of the better-evidenced herbal options for women's hormonal support.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.