Absorption Enhancer
BioPerine (Black Pepper Extract)
Also known as: Piperine, Black pepper extract, BioPerine
Patented black pepper extract containing piperine. Enhances absorption of many supplements including curcumin, CoQ10, and vitamins.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every BioPerine (Black Pepper Extract) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Nutricost KSM-66 Capsules | 96 A | $0.28 |
| 2 | Doctor's Best High Absorption CoQ10 with BioPerine, 300 mg, 90 Veggie Softgels | 95 A | $0.41 |
| 3 | Doctor's Best High Absorption CoQ10 with BioPerine, 100 mg, 60 Veggie Caps | 95 A | $0.22 |
| 4 | Nutricost DIM Capsules | 94 A | $0.17 |
| 5 | Nutricost L-Tryptophan Capsules | 94 A | $0.15 |
| 6 | NOW Foods Magnesium Glycinate with BioPerine | 93 A | $0.22 |
| 7 | Transparent Labs Fat Burner | 92 A | $0.92 |
| 8 | Pure Encapsulations Curcumin 500 with Bioperine | 92 A | $0.85 |
| 9 | Transparent Labs BULK Pre-Workout | 90 A | $1.67 |
| 10 | Nutricost Turmeric Capsules | 90 A | $0.42 |
| 11 | NutraBio Curcumin Advanced | 90 A | $1.23 |
| 12 | Nutricost Pre-Workout For Women Powder | 89 A | $0.73 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much BioPerine (Black Pepper Extract) should I take?
The typical range is 5-20mg daily. Safe long-term
When should I take BioPerine (Black Pepper Extract)?
With the supplement being enhanced. With the target supplement.
Which form of BioPerine (Black Pepper Extract) is best?
Capsule (standalone) — Rare standalone. Other forms in the catalog: Added to formulas.
Is BioPerine (Black Pepper Extract) safe?
Commonly reported: GI upset possible, Burning sensation. Serious warnings: Increases absorption of medications too. Affects drug metabolism
Which BioPerine (Black Pepper Extract) supplement scores highest?
Nutricost KSM-66 Capsules, at 96/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Absorption enhancement
- Bioavailability
- Thermogenesis
How it works
- Inhibits glucuronidation
- Slows hepatic metabolism
- Increases intestinal absorption
- Thermogenic effects
Dosage
- Typical range
- 5-20mg daily
- Timing
- With the supplement being enhanced
- With food
- With the target supplement
- Duration
- Safe long-term
- Special populations
- Anyone taking curcumin, CoQ10, etc.
Forms
- Capsule (standalone)
- Added to formulas
Safety
Common side effects
- GI upset possible
- Burning sensation
Contraindications
- GI ulcers
- GERD
Products containing BioPerine (Black Pepper Extract)
Top-scoring supplements in our catalog that list BioPerine (Black Pepper Extract) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Well-established absorption enhancer for many compounds
Grade A: Multiple well-designed human trials support the main claims.
Related in Absorption Enhancer
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.