Vitamin
Benfotiamine
Also known as: Lipid-soluble thiamine, S-benzoylthiamine
B
Evidence
Fat-soluble thiamine derivative with superior bioavailability. Particularly effective for diabetic neuropathy and AGE reduction.
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Daily target & upper limit
1.2 mg / dayBenfotiamine has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Benfotiamine dosage reference →Primary uses
- Diabetic neuropathy
- AGE reduction
- Nerve health
- Blood sugar support
How it works
- 5x better absorbed than thiamine
- Blocks AGE formation
- Activates transketolase
- Protects endothelial cells
Dosage
- Typical range
- 150-600 mg daily
- Timing
- With meals
- With food
- Yes
- Duration
- Benefits develop over weeks
- Special populations
- Diabetics, neuropathy
Forms
- Capsule
Safety
Common side effects
- Well tolerated
Contraindications
- None
Evidence notes
Superior bioavailability for neuropathy
Grade B: Some human trials support key claims; further confirmation needed.
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