SAM-e Complete 200 mg Tablets
Scored by the Formulate Research Team · Last reviewed July 2026
Score Breakdown
Three factors carry this score; three more are checked separately and can only take points away. Hover or tap to see what drove each one.
Ingredients per Serving
| Ingredient | Amount |
|---|---|
| SAM-e | 400 mg |
Certifications & Testing
Other Ingredients
S-Adenosylmethionine Tosylate Disulfate, Cellulose Gel, Mannitol, Methacrylic Acid Copolymer, Magnesium Stearate, Silicon Dioxide, Triethyl Citrate, Color added, Sodium Starch Glycolate
Recommended Use
Suggested use: Start with 2 tablets per day. For easier swallowing, take with water before and during ingestion. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of t
Warnings
Foil blister pack ensures safety and freshness. Do not use if tamper evident printed foil seal over tablets is broken. Store in a cool, dry place, out of reach of children. Caution: People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision. If
Frequently Asked Questions
What is Nature Made SAM-e Complete 200 mg Tablets's Formulate score?
Nature Made SAM-e Complete 200 mg Tablets scores 90 out of 100 (grade A) on Formulate's ingredient-level rubric: clinical evidence, dose accuracy and bioavailability carry the score, while manufacturing, transparency and safety are checked separately and can only deduct.
Is Nature Made SAM-e Complete 200 mg Tablets worth it?
Nature Made SAM-e Complete 200 mg Tablets scores 90/100 (grade A). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.
What's in Nature Made SAM-e Complete 200 mg Tablets?
Each serving contains SAM-e (400 mg). Serving size: 2 Tablet(s). 30 servings per container.
How do I take sam-e complete 200 mg tablets?
Suggested use: Start with 2 tablets per day. For easier swallowing, take with water before and during ingestion. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablet (maximum 1600 mg/day) until benefits are achieved.
Who makes SAM-e Complete 200 mg Tablets?
SAM-e Complete 200 mg Tablets is made by Nature Made. See Formulate's full grade and product lineup for Nature Made on its brand page.
Is Nature Made SAM-e Complete 200 mg Tablets third-party tested?
Nature Made lists the following certifications and testing for this product: Gluten-Free.
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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.