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Doctor's Best SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets

SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets

81A-
Grade A- · tablet · 60 servings · $33.99
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Scored by the Formulate Research Team · Last reviewed July 2026

Score Breakdown

Three factors carry this score; three more are checked separately and can only take points away. Hover or tap to see what drove each one.

Evidence Qualityweight 40%
95/ 100
Dose Adequacyweight 35%
95/ 100
Form/Bioavailabilityweight 25%
80/ 100
Transparencyweight 0%
90/ 100
Safety/Redundancyweight 0%
100/ 100
Manufacturing Qualityweight 0%
50/ 100

Ingredients per Serving

IngredientAmount
SAM-e200 mg

Certifications & Testing

Non-GMOGluten-FreeVegetarian

Other Ingredients

Microcrystalline Cellulose, Magnesium Silicate, Flake Shellac dewaxed, Magnesium Stearate, Stearic Acid, Magnesium Hydroxide, Glycerol, Silica, Arginine, Sodium Alginate, Calcium Oxide

Recommended Use

MorningOn an empty stomach

Suggested Adult Use: Take 1 tablet twice daily between meals, or as recommended by a nutritionally informed physician. Do not chew or crush tablet.

Warnings

Warning: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAM-e. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Frequently Asked Questions

What is Doctor's Best SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets's Formulate score?

Doctor's Best SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets scores 81 out of 100 (grade A-) on Formulate's ingredient-level rubric: clinical evidence, dose accuracy and bioavailability carry the score, while manufacturing, transparency and safety are checked separately and can only deduct.

Is Doctor's Best SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets worth it?

Doctor's Best SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets scores 81/100 (grade A-). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.

What's in Doctor's Best SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets?

Each serving contains SAM-e (200 mg). Serving size: 1 Tablet(s). 60 servings per container.

How do I take sam-e, 200 mg per serving, 60 enteric coated tablets?

Suggested Adult Use: Take 1 tablet twice daily between meals, or as recommended by a nutritionally informed physician. Do not chew or crush tablet.

Who makes SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets?

SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets is made by Doctor's Best. See Formulate's full grade and product lineup for Doctor's Best on its brand page.

Is Doctor's Best SAM-e, 200 mg Per Serving, 60 Enteric Coated Tablets third-party tested?

Doctor's Best lists the following certifications and testing for this product: Non-GMO, Gluten-Free, Vegetarian.

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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.