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Ranked by evidence

Best Nootropics Supplements

The 10 highest-scoring nootropics supplements in Formulate's catalog, ranked by the same automated rubric we apply to every product: ingredient dose, bioavailable form, label transparency, safety, and third-party testing. No sponsorships, no pay-to-play.

Scored by the Formulate Research Team · Last reviewed July 2026

  1. 1
    NOW Foods
    CurcuBrain

    Strongest on dose adequacy (100/100).

    Find on Amazon
    97A
  2. 2
    Nootropics Depot
    Alpha GPC Capsules

    Buy Alpha GPC Capsules | Nootropics Depot is the #1 most trusted source for high quality Alpha GPC Capsules. See Alpha GPC dosage, uses and more.

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    96A
  3. 3
    Nootropics Depot
    Alpha GPC Powder

    Buy Alpha-GPC Powder - Nootropics Depot is the #1 most trusted source for high quality Alpha-GPC powder. Read reviews, learn uses and benefits. 10% off first order

    Find on Amazon
    96A
  4. 4
    Jarrow Formulas
    Citicoline (CDP Choline)

    Strongest on form/bioavailability (100/100).

    Find on Amazon
    96A
  5. 5
    Life Extension
    Citicoline CDP-Choline

    Strongest on form/bioavailability (100/100).

    Find on Amazon
    96A
  6. 6
    Nutricost
    CDP Choline Capsules

    300mg Of CDP Choline In Every (Vegetarian) Capsule Easy To Swallow 60/120 Capsules in Every Bottle (1 Capsule Servings) Manufactured In a GMP Compliant, FDA Registered Facility…

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    95A
  7. 7
    Thorne
    Phosphatidylserine

    Promotes healthy brain function, supports memory and focus, and modulates cortisol during stress* Thorne's Phosphatidylserine contains phosphatidylserine (PS), the primary phosp…

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    95A
  8. 8
    Nootropics Depot
    Bacognize® Bacopa monnieri Capsules

    Buy BaCognize Bacopa Monnieri Capsules - Nootropics Depot is the #1 most trusted source for high quality Bacopa Monnieri capsules. Read reviews, learn uses and benefits.

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    94A
  9. 9
    Pure Encapsulations
    Phosphatidylcholine (sunflower)

    Strongest on transparency (100/100).

    Find on Amazon
    94A
  10. 10
    Nutricost
    Alpha GPC Capsules

    Nutricost Alpha GPC Capsules — capsule format. Contains Alpha GPC. Supports: Cognition, Energy, Mood. GMP Certified, FDA Registered, Third Party Tested certified.

    Find on Amazon
    92A
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Frequently asked questions

What is the best nootropics supplement?

NOW Foods CurcuBrain is Formulate's highest-scoring nootropics supplement at 97/100 (grade A). Strongest on dose adequacy (100/100).

How does Formulate rank nootropics supplements?

Each product is scored 0–100 by the same automated rubric. Clinical evidence, dose accuracy and bioavailable form carry the score; manufacturing, label transparency and safety are checked separately and can only cost points. Rankings reflect the formula on the label — not advertising or sponsorships.

How many nootropics supplements were compared?

This ranking shows the top 10 nootropics products Formulate has scored. Browse the full catalog for every product and its breakdown.

Best supplements by category

Best MineralsBest MultivitaminsBest Amino AcidsBest AdaptogensBest Fish Oil & OmegasBest BotanicalsBest B VitaminsBest Antioxidants

How these are ranked

Every nootropics product is scored on dose accuracy, ingredient form, certifications, transparency, and third-party testing — the same rubric across the whole catalog. See the methodology page for the full breakdown, or browse every supplement.

Educational only. Rankings reflect product formulation quality, not personalized medical advice. Talk to a qualified healthcare provider before starting a new supplement, especially if you take medication.