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blood pressure medications and licorice

Licorice raises blood pressure, opposing medication

What's happening

Glycyrrhizin in licorice causes sodium retention and potassium loss (pseudoaldosteronism), raising blood pressure. Can counteract all BP medications. As little as 50g/day of licorice candy (if containing real licorice root) can cause hypertension.

Recommendation

Avoid licorice supplements and excessive licorice candy on BP medications.

Timing

Effect persists 2 weeks after stopping licorice

Sources

  • American Journal of Hypertension
  • PMID: 11693621
  • BMJ Case Reports

Frequently Asked Questions

Can I take blood pressure medications and licorice together?

Licorice raises blood pressure, opposing medication. Avoid licorice supplements and excessive licorice candy on BP medications.

How should I time blood pressure medications and licorice?

Effect persists 2 weeks after stopping licorice

Is this interaction dangerous?

This interaction is rated “Warning” by Formulate. Glycyrrhizin in licorice causes sodium retention and potassium loss (pseudoaldosteronism), raising blood pressure. Can counteract all BP medications. As little as 50g/day of licorice candy (if containing real licorice root) can cause hypertension.

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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.