Glycyrrhizin in licorice causes sodium retention and potassium loss (pseudoaldosteronism), raising blood pressure. Can counteract all BP medications. As little as 50g/day of licorice candy (if containing real licorice root) can cause hypertension.
Recommendation
Avoid licorice supplements and excessive licorice candy on BP medications.
Timing
Effect persists 2 weeks after stopping licorice
Sources
— American Journal of Hypertension
— PMID: 11693621
— BMJ Case Reports
Frequently Asked Questions
Can I take blood pressure medications and licorice together?
Licorice raises blood pressure, opposing medication. Avoid licorice supplements and excessive licorice candy on BP medications.
How should I time blood pressure medications and licorice?
Effect persists 2 weeks after stopping licorice
Is this interaction dangerous?
This interaction is rated “Warning” by Formulate. Glycyrrhizin in licorice causes sodium retention and potassium loss (pseudoaldosteronism), raising blood pressure. Can counteract all BP medications. As little as 50g/day of licorice candy (if containing real licorice root) can cause hypertension.
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