Like statins, some beta blockers (propranolol, metoprolol) can inhibit CoQ10 biosynthesis. Not as well-documented as statin depletion, but supplementation is often considered for long-term users with fatigue.
Recommendation
100-200mg ubiquinol daily is reasonable for long-term beta blocker users — especially if experiencing exercise intolerance.
Timing
Take with a fat-containing meal for absorption
Sources
— Biochemical and Biophysical Research Communications
— PMID: 4146484
Frequently Asked Questions
Can I take beta blocker and coq10 together?
Beta blockers may deplete CoQ10. 100-200mg ubiquinol daily is reasonable for long-term beta blocker users — especially if experiencing exercise intolerance.
How should I time beta blocker and coq10?
Take with a fat-containing meal for absorption
Is this interaction dangerous?
This interaction is rated “Info” by Formulate. Like statins, some beta blockers (propranolol, metoprolol) can inhibit CoQ10 biosynthesis. Not as well-documented as statin depletion, but supplementation is often considered for long-term users with fatigue.
Want to check your whole stack?
The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.