Antioxidant
Sesanum indicum Extract (Sesame Seed) - 70% Sesamins
Also known as: sesame seed extract, sesamins, sesamin, sesamol
Sesame seed extract standardized to 70% sesamins is a lignan-rich antioxidant derived from sesame seeds with preliminary evidence for antioxidant and anti-inflammatory effects. Human clinical research remains limited, with most supportive data from in vitro and animal studies.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Sesanum indicum Extract (Sesame Seed) - 70% Sesamins product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Life Extension Super Omega-3 Plus | 75 B+ | $0.66 |
| 2 | Life Extension Super Omega-3 | 71 B | $0.46 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Sesanum indicum Extract (Sesame Seed) - 70% Sesamins should I take?
The typical range is 300-600 mg daily (standardized to 70% sesamins). No established minimum duration; effects may take 4-8 weeks to manifest
When should I take Sesanum indicum Extract (Sesame Seed) - 70% Sesamins?
With meals for optimal absorption. Recommended; sesamins are fat-soluble compounds.
Which form of Sesanum indicum Extract (Sesame Seed) - 70% Sesamins is best?
Powder. Other forms in the catalog: Capsule, Extract.
Is Sesanum indicum Extract (Sesame Seed) - 70% Sesamins safe?
Commonly reported: Generally well-tolerated, Rare: gastrointestinal upset, Rare: allergic reactions (sesame allergy).
Which Sesanum indicum Extract (Sesame Seed) - 70% Sesamins supplement scores highest?
Life Extension Super Omega-3 Plus, at 75/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Antioxidant support
- Anti-inflammatory support
- Cognitive function
- Cardiovascular health
- Cholesterol management
How it works
- Lignan-based antioxidant activity via free radical scavenging
- CYP3A4 and CYP2C9 enzyme modulation
- Anti-inflammatory signaling pathway support
- Lipid peroxidation reduction
Dosage
- Typical range
- 300-600 mg daily (standardized to 70% sesamins)
- Timing
- With meals for optimal absorption
- With food
- Recommended; sesamins are fat-soluble compounds
- Duration
- No established minimum duration; effects may take 4-8 weeks to manifest
- Special populations
- Pregnant/nursing women should consult healthcare provider; limited safety data in pediatric populations
Forms
- Powder· 70/100
- Capsule· 70/100
- Extract· 70/100
Safety
Common side effects
- Generally well-tolerated
- Rare: gastrointestinal upset
- Rare: allergic reactions (sesame allergy)
Contraindications
- Sesame allergy or sensitivity
- Concurrent use with immunosuppressants (potential sesame immunogenicity)
Products containing Sesanum indicum Extract (Sesame Seed) - 70% Sesamins
Top-scoring supplements in our catalog that list Sesanum indicum Extract (Sesame Seed) - 70% Sesamins on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Limited human RCT evidence; most studies are in vitro or animal models. A few small human studies show modest benefits for antioxidant status and lipid profiles, but robust clinical efficacy data is lacking. Standardization to sesamins is appropriate, but clinical outcomes require additional investigation.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.