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Adaptogen

Rhodiola rosea Extract (root) - Salidroside

Also known as: Rhodiola rosea, Golden Root, Rose Root, Salidroside-standardized Rhodiola

B
Evidence

Rhodiola rosea standardized to salidroside alone is a single-marker extract of this well-researched adaptogenic herb, providing one of the two major bioactive compound classes for stress resilience and cognitive support. This formulation emphasizes one of the key active constituents.

Primary uses

  • Stress and anxiety reduction
  • Mental fatigue and focus
  • Physical endurance
  • Mood support
  • Cognitive performance

How it works

  • Modulation of HPA axis and stress hormone regulation
  • Monoamine neurotransmitter enhancement
  • Cellular energy and ATP production
  • Antioxidant neuroprotection
  • Anti-inflammatory effects

Dosage

Typical range
300-600 mg daily (standardized extract)
Timing
Morning to early afternoon; avoid evening dosing
With food
May be taken with or without food; consistent timing recommended
Duration
Effects typically observed within 1-2 weeks; appropriate for long-term use. Adaptogenic benefits compound with regular use.
Special populations
Generally well-tolerated; use caution in pregnancy/lactation and bipolar disorder

Forms

  • Extract (salidroside-standardized)· 70/100

Safety

Common side effects

  • Mild insomnia (if taken late)
  • Mild headache (rare, early use)
  • Mild nervousness (uncommon)

Contraindications

  • Bipolar disorder (may worsen mood cycling)
  • Pregnancy and lactation (insufficient safety data)
  • Acute mania or psychotic episodes

Evidence notes

Solid RCT evidence for R. rosea; however, this single-marker (3% salidroside only) formulation lacks rosavins, which are also identified as important bioactive compounds in clinical research. Salidroside alone supports efficacy but a dual-standardized form may offer more comprehensive benefits.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.