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Adaptogen

Rhodiola rosea Extract (root) - Salidroside

Also known as: Rhodiola rosea, Golden Root, Rose Root, Salidroside-standardized Rhodiola

B
Evidence

Rhodiola rosea standardized to salidroside alone is a single-marker extract of this well-researched adaptogenic herb, providing one of the two major bioactive compound classes for stress resilience and cognitive support. This formulation emphasizes one of the key active constituents.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Stress and anxiety reduction
  • Mental fatigue and focus
  • Physical endurance
  • Mood support
  • Cognitive performance

How it works

  • Modulation of HPA axis and stress hormone regulation
  • Monoamine neurotransmitter enhancement
  • Cellular energy and ATP production
  • Antioxidant neuroprotection
  • Anti-inflammatory effects

Dosage

Typical range
300-600 mg daily (standardized extract)
Timing
Morning to early afternoon; avoid evening dosing
With food
May be taken with or without food; consistent timing recommended
Duration
Effects typically observed within 1-2 weeks; appropriate for long-term use. Adaptogenic benefits compound with regular use.
Special populations
Generally well-tolerated; use caution in pregnancy/lactation and bipolar disorder

Forms

  • Extract (salidroside-standardized)· 70/100

Safety

Common side effects

  • Mild insomnia (if taken late)
  • Mild headache (rare, early use)
  • Mild nervousness (uncommon)

Contraindications

  • Bipolar disorder (may worsen mood cycling)
  • Pregnancy and lactation (insufficient safety data)
  • Acute mania or psychotic episodes

Evidence notes

Solid RCT evidence for R. rosea; however, this single-marker (3% salidroside only) formulation lacks rosavins, which are also identified as important bioactive compounds in clinical research. Salidroside alone supports efficacy but a dual-standardized form may offer more comprehensive benefits.

Grade B: Some human trials support key claims; further confirmation needed.

Cited research for Rhodiola rosea Extract (root) - Salidroside

Clinical studies referenced across Formulate guides that mention rhodiola rosea extract (root) - salidroside. Each links to the full study page with PubMed source + the guides that cite it.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.