Amino Acid

L-Methionine

Also known as: Methionine

Evidence

Essential sulfur amino acid. Precursor to cysteine, taurine, and SAM-e.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Sulfur source
SAM-e precursor
Liver support
Detox

How it works

Precursor to cysteine and taurine
Methyl donor (as SAM-e)
Antioxidant support

Dosage

Typical range: 500-1500mg daily
Timing: Between meals
With food: Optional
Duration: Moderate duration
Special populations: Liver support, sulfur support

Forms

Capsules
Powder

Safety

Common side effects

GI upset

Contraindications

High homocysteine
Schizophrenia

Products containing L-Methionine

Top-scoring supplements in our catalog that list L-Methionine on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Thorne

Amino Complex - Berry

Thorne

Amino Complex - Lemon

Thorne

Amino Complex

See all products →

Evidence notes

Essential amino acid

Grade B: Some human trials support key claims; further confirmation needed.

Related in Amino Acid

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.