Hormone
Melatonin (GERD Support)
Sleep hormone that also supports lower esophageal sphincter function and may help GERD symptoms.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Melatonin (GERD Support) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne Melaton-3™ | 92 A | $0.27 |
| 2 | Thorne Melaton-5™ | 92 A | $0.37 |
| 3 | Pure Encapsulations Melatonin 3 mg | 92 A | $0.38 |
| 4 | Pure Encapsulations Melatonin-SR | 92 A | $0.38 |
| 5 | Pure Encapsulations Melatonin 20 mg | 92 A | $0.56 |
| 6 | Pure Encapsulations Melatonin liquid | 92 A | $1.23 |
| 7 | Pure Encapsulations Melatonin 0.5 mg | 92 A | $0.21 |
| 8 | Life Extension Fast-Acting Liquid Melatonin - Citrus-Vanilla | 92 A | $0.15 |
| 9 | NutraBio Melatonin (3mg) | 92 A | $0.14 |
| 10 | NOW Foods Extra Strength Melatonin | 91 A | $0.13 |
| 11 | NOW Foods Liquid Melatonin | 91 A | $0.11 |
| 12 | NOW Foods Melatonin | 91 A | $0.07 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Melatonin (GERD Support) should I take?
The typical range is 3-6mg at bedtime for GERD (higher than sleep doses). Ongoing as needed
When should I take Melatonin (GERD Support)?
Bedtime. Either way.
Which form of Melatonin (GERD Support) is best?
Capsules/tablets — Higher doses for GERD. Other forms in the catalog: Sublingual.
Is Melatonin (GERD Support) safe?
Commonly reported: Morning grogginess, Vivid dreams, Headache. Serious warnings: May affect blood pressure, Drowsiness. Safe at normal doses
Which Melatonin (GERD Support) supplement scores highest?
Thorne Melaton-3™, at 92/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- GERD support
- LES function
- Sleep
- GI motility
How it works
- Strengthens lower esophageal sphincter
- Reduces gastric acid secretion
- Antioxidant in esophagus
- Supports GI motility
Dosage
- Typical range
- 3-6mg at bedtime for GERD (higher than sleep doses)
- Timing
- Bedtime
- With food
- Either way
- Duration
- Ongoing as needed
- Special populations
- GERD, especially nighttime reflux
Forms
- Capsules/tablets
- Sublingual
Safety
Common side effects
- Morning grogginess
- Vivid dreams
- Headache
Contraindications
- Autoimmune diseases (theoretical)
- Depression (may worsen in some)
Products containing Melatonin (GERD Support)
Top-scoring supplements in our catalog that list Melatonin (GERD Support) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Emerging evidence for GERD at higher doses
Grade B: Some human trials support key claims; further confirmation needed.
Related in Hormone
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.