Hormone
Melatonin (GERD Support)
B
Evidence
Sleep hormone that also supports lower esophageal sphincter function and may help GERD symptoms.
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Primary uses
- GERD support
- LES function
- Sleep
- GI motility
How it works
- Strengthens lower esophageal sphincter
- Reduces gastric acid secretion
- Antioxidant in esophagus
- Supports GI motility
Dosage
- Typical range
- 3-6mg at bedtime for GERD (higher than sleep doses)
- Timing
- Bedtime
- With food
- Either way
- Duration
- Ongoing as needed
- Special populations
- GERD, especially nighttime reflux
Forms
- Capsules/tablets
- Sublingual
Safety
Common side effects
- Morning grogginess
- Vivid dreams
- Headache
Contraindications
- Autoimmune diseases (theoretical)
- Depression (may worsen in some)
Products containing Melatonin (GERD Support)
Top-scoring supplements in our catalog that list Melatonin (GERD Support) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Emerging evidence for GERD at higher doses
Grade B: Some human trials support key claims; further confirmation needed.
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