Performance
Huperzine A (for Performance)
Also known as: Huperzia serrata extract, Huperzine A
Acetylcholinesterase inhibitor extending acetylcholine action. Enhances focus.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Focus
- Memory
- Mind-muscle connection
How it works
- Inhibits acetylcholine breakdown
- Extends cholinergic signaling
- Neuroprotective
Dosage
- Typical range
- 50-200mcg
- Timing
- Pre-workout or morning
- With food
- Either
- Duration
- Cycle 2-4 weeks on/off
- Special populations
- Focus and memory
Forms
- Capsule
Safety
Common side effects
- Nausea
- Diarrhea
- Sweating
- Muscle twitching
Contraindications
- Heart rhythm issues
- GI obstruction
- Asthma
Evidence notes
Good evidence for cognitive effects
Grade B: Some human trials support key claims; further confirmation needed.
Related in Performance
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.