Mineral
Chloride
Also known as: Chloride ion, Cl-
Essential electrolyte mineral that works with sodium and potassium to maintain fluid balance, nerve transmission, and stomach acid production.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Chloride product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | BulkSupplements Glucosamine Sulfate Capsules | 95 A | $0.05 |
| 2 | Double Wood Magnesium Chloride Supplement | 91 A | $0.22 |
| 3 | Pure Encapsulations NR Longevity | 87 A | $2.17 |
| 4 | Thorne Catalyte® | 85 A- | $1.13 |
| 5 | Nutricost Sodium Chloride Tablets | 84 A- | $0.07 |
| 6 | Thorne Electrolytes - Mango Limeade | 82 A- | $1.33 |
| 7 | Thorne Electrolytes - Variety Pack | 82 A- | $0.83 |
| 8 | Thorne Electrolytes - Watermelon | 82 A- | $1.20 |
| 9 | Thorne Daily Electrolytes - Blood Orange | 82 A- | $1.20 |
| 10 | Country Life Acetyl L-Carnitine Caps 500 mg | 80 A- | $0.40 |
| 11 | Integrative Therapeutics Glucosamine Sulfate | 79 B+ | $0.72 |
| 12 | Double Wood DHM 1000 Supplement | 78 B+ | $2.00 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Chloride should I take?
The typical range is 2300 mg daily (adequate intake). Daily requirement
When should I take Chloride?
Throughout day with fluids. With or without.
Which form of Chloride is best?
Sodium chloride — Most common (table salt). Other forms in the catalog: Potassium chloride, Magnesium chloride.
Is Chloride safe?
Commonly reported: Well tolerated at normal doses. Serious warnings: Excess can raise blood pressure (with sodium). Caution in kidney disease
Which Chloride supplement scores highest?
BulkSupplements Glucosamine Sulfate Capsules, at 95/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Fluid balance
- Electrolyte replenishment
- Digestive support
- Nerve function
How it works
- Major extracellular anion
- Required for stomach acid (HCl) production
- Works with sodium to maintain osmotic pressure
- Essential for carbon dioxide transport in blood
Dosage
- Typical range
- 2300 mg daily (adequate intake)
- Timing
- Throughout day with fluids
- With food
- With or without
- Duration
- Daily requirement
- Special populations
- Athletes may need more during exercise
Forms
- Sodium chloride
- Potassium chloride
- Magnesium chloride
Safety
Common side effects
- Well tolerated at normal doses
Contraindications
- Severe kidney disease
- Hyperchloremia
Products containing Chloride
Top-scoring supplements in our catalog that list Chloride on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Essential mineral with well-established physiological roles
Grade A: Multiple well-designed human trials support the main claims.
Cited research for Chloride
Clinical studies referenced across Formulate guides that mention chloride. Each links to the full study page with PubMed source + the guides that cite it.
Related in Mineral
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.