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Herbal Extract

Caralluma Fimbriata Extract

Also known as: Caralluma fimbriata, Indian cactus, Slimall, Caralluma extract

C
Evidence

Caralluma fimbriata is a succulent plant traditionally used in Indian cuisine with preliminary evidence suggesting potential appetite-suppressing properties. Limited human clinical trials support claims of weight management benefits, with most studies being small and short-term.

Primary uses

  • Appetite suppression
  • Weight management support
  • Satiety enhancement

How it works

  • Potential appetite regulation via CNS signaling
  • May influence satiety hormones
  • Possible AMPK activation (animal studies)

Dosage

Typical range
500-1000 mg daily
Timing
Typically divided into 2 doses (morning and evening)
With food
Can be taken with or without food; some sources recommend before meals
Duration
Human studies examined 8-12 week periods; long-term safety data limited
Special populations
Insufficient safety data in pregnancy/lactation; use caution in diabetics (may affect blood sugar)

Forms

  • Extract powder· 70/100
  • Standardized extract· 70/100

Safety

Common side effects

  • Mild gastrointestinal discomfort
  • Nausea
  • Dry mouth
  • Headache (rare)

Contraindications

  • Pregnancy and lactation (insufficient safety data)
  • Concurrent use with SGLT2 inhibitors (theoretical risk for euglycemic DKA)
  • Severe kidney or liver disease

Evidence notes

Only a few small human clinical trials exist (mostly 8-12 weeks). Most positive studies are industry-sponsored. Mechanism remains unclear. Insufficient evidence for strong recommendation; more rigorous long-term RCTs needed for higher grading.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.