SAMe - 400mg
Scored by the Formulate Research Team · Last reviewed July 2026
Score Breakdown
Formulate scores every product across six weighted dimensions. Each dimension is graded independently — hover or tap to see what drove each component.
Ingredients per Serving
| Ingredient | Amount |
|---|---|
| S-Adenosyl Methionine | 400 mg |
Certifications & Testing
Other Ingredients
Microcrystalline Cellulose, Hypromellose Acetate Succinate, Stearic Acid, Triethyl Citrate, Riboflavin, Glyceryl Behenate, Magnesium Stearate, Silicon Dioxide, Mannitol, Sodium Starch Glycolate
Recommended Use
Suggested Use: Adults take 1 tablet once a day on an empty stomach or as directed by your qualified healthcare professional.
Warnings
Warning: Do not use if pregnant or nursing. Individuals with Parkinson’s disease, bi-polar disorder, or manic depression should not use this product. May cause gastrointestinal upset in some persons. Consult a healthcare professional before using this product if you are under the age of 18, are taking medication (antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and MAO inhibitors)
Frequently Asked Questions
What is Jarrow Formulas SAMe - 400mg's Formulate score?
Jarrow Formulas SAMe - 400mg scores 80 out of 100 (grade A-) on Formulate's ingredient-level rubric: clinical evidence, dose accuracy and bioavailability carry the score, while manufacturing, transparency and safety are checked separately and can only deduct.
Is Jarrow Formulas SAMe - 400mg worth it?
Jarrow Formulas SAMe - 400mg scores 80/100 (grade A-). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.
What's in Jarrow Formulas SAMe - 400mg?
Each serving contains S-Adenosyl Methionine (400 mg). Serving size: 1 Tablet(s). 60 servings per container.
How do I take same - 400mg?
Suggested Use: Adults take 1 tablet once a day on an empty stomach or as directed by your qualified healthcare professional.
Who makes SAMe - 400mg?
SAMe - 400mg is made by Jarrow Formulas. See Formulate's full grade and product lineup for Jarrow Formulas on its brand page.
Is Jarrow Formulas SAMe - 400mg third-party tested?
Jarrow Formulas lists the following certifications and testing for this product: Gluten-Free, Non-GMO, Vegan, Vegetarian, Dairy-Free.
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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.