Primary Research · 2013
Meta-analysis: melatonin for the treatment of primary sleep disorders
Ferracioli-Oda E, Qawasmi A, Bloch MH · PLOS ONE, 2013
Key finding
Meta-analysis of 19 RCTs (n=1,683) found melatonin reduced sleep-onset latency by ~7 minutes, increased total sleep time by ~8 minutes, and improved overall sleep quality — small but consistent effect across populations.
About the supplement
Melatonin
Dose · mechanism · evidence grade · safety →
Read the paper
Open on PubMedhttps://pubmed.ncbi.nlm.nih.gov/23691095/
About this page
Formulate maintains a registry of clinical studies cited across its guides and evidence grades. This page links the study metadata to the content that cites it — one canonical entry per landmark study.
The full citation chain is public so readers can verify claims without hunting through individual guide pages. Browse all cited studies →
Note: Study summaries on this page are editorial interpretations of the research. Always consult the primary source before drawing clinical conclusions.