Primary Research · 2014
Warfarin Interactions with Medicinal Herbs
Primary literature · Systematic review, 2014
Key finding
Dong quai contains natural coumarin derivatives (ferulic acid, osthole) with documented antithrombotic and platelet-inhibitory effects. Animal steady-state studies show dong quai significantly increased prothrombin time WITHOUT affecting warfarin concentration - suggesting pharmacodynamic (not pharmacokinetic) interaction. Recommends informing patients of the potential hazard.
Read the paper
Open sourcehttps://journals.sagepub.com/doi/pdf/10.1177/1934578X1400900835
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