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Antioxidant

Wolfberry Extract (Lycium barbarum)

Also known as: Goji berry, Goji berry extract, Lycium barbarum fruit, Chinese wolfberry

C
Evidence

Wolfberry (goji berry) is a traditional Chinese fruit rich in polysaccharides, carotenoids, and antioxidants with preliminary evidence for immune support and eye health. Most human studies are small or conducted in Asian populations, limiting generalizability of findings.

Primary uses

  • Antioxidant support
  • Eye health and vision
  • Immune function
  • Traditional vitality support

How it works

  • Polysaccharide and carotenoid-mediated antioxidant activity
  • Potential immune cell modulation
  • Lutein and zeaxanthin content for ocular protection

Dosage

Typical range
1–15 g daily of whole fruit or dried equivalent; 300–500 mg of concentrated extract
Timing
With meals to optimize absorption of fat-soluble carotenoids
With food
Recommended; fat-soluble nutrient content benefits from dietary fat
Duration
Traditional use suggests ongoing supplementation; typical studies range 4–12 weeks
Special populations
Generally recognized as safe in food form; pregnant/nursing women should consult healthcare provider before supplemental use

Forms

  • Powder extract· 70/100
  • Dried fruit· 70/100
  • Concentrated extract· 70/100
  • Capsule· 70/100
  • Liquid extract· 70/100

Safety

Common side effects

  • Mild digestive upset in sensitive individuals
  • Rare allergic reactions

Contraindications

  • Potential interaction with blood-thinning medications (theoretical; use with caution)
  • May cause diarrhea or stomach upset at very high doses
  • Caution in individuals with nightshade sensitivity

Evidence notes

Moderate preliminary evidence from small human trials and in vitro studies. Polysaccharide and carotenoid content is well-documented, but clinical efficacy in Western populations remains limited. Most robust data from traditional use and animal models; human RCTs are sparse and often published in regional journals.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.