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Fatty Acid

Wild Cod Liver Oil

Also known as: cod liver oil, CLO, gadidae oil

B
Evidence

A nutrient-dense oil from wild Atlantic cod (Gadus morhua) livers, naturally rich in EPA, DHA, vitamin A, and vitamin D3. Traditionally used for joint health and immune support.

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Primary uses

  • omega-3 supplementation
  • joint and bone support
  • immune function
  • vision and skin health

How it works

  • provides preformed EPA/DHA reducing need for conversion
  • supplies fat-soluble vitamins (A and D3)
  • reduces systemic inflammation through omega-3 content
  • supports membrane integrity

Dosage

Typical range
1-3 grams daily of cod liver oil (providing 180-540 mg EPA and 120-360 mg DHA approximately)
Timing
with meals containing additional fat for optimal absorption
With food
recommended to reduce GI upset and improve absorption
Duration
safe for long-term continuous use; fat-soluble vitamins accumulate over time
Special populations
pregnant women should verify vitamin A content does not exceed safe limits; individuals on anticoagulants should monitor intake

Forms

  • liquid oil· 70/100
  • capsules· 70/100
  • softgels· 70/100

Safety

Common side effects

  • fishy aftertaste
  • mild GI upset
  • nausea (especially on empty stomach)

Contraindications

  • allergy to fish or shellfish
  • bleeding disorders (high-dose)
  • scheduled surgery (may increase bleeding risk)

Evidence notes

Cod liver oil has good clinical evidence for omega-3 and vitamin benefits, though newer purified fish oils have more extensive RCT data. Traditional use and composition well-documented.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.