Herbal Extract
Watercress Extract (Nasturtium officinale)
Also known as: Nasturtium officinale, watercress powder, watercress whole herb extract
Watercress is a nutrient-dense cruciferous vegetable containing glucosinolates, vitamins, and minerals with preliminary evidence for antioxidant and anti-inflammatory effects. Most human studies involve whole watercress consumption rather than isolated extracts, limiting conclusions about extract efficacy.
Primary uses
- Antioxidant support
- Anti-inflammatory effects
- General nutritional supplementation
- Cardiovascular health support
How it works
- Glucosinolate metabolism to isothiocyanates with potential phase II enzyme induction
- Phenolic and flavonoid antioxidant activity
- Potential inhibition of oxidative stress pathways
Dosage
- Typical range
- 500–2,000 mg daily (powder form)
- Timing
- Any time of day
- With food
- Can be taken with or without food; taking with meals may improve absorption of fat-soluble compounds
- Duration
- No established optimal duration; typically used long-term for nutritional support
- Special populations
- Generally well-tolerated; avoid very high intakes in pregnancy due to limited safety data
Forms
- Powder· 70/100
- Whole herb extract· 70/100
Safety
Common side effects
- Generally well-tolerated
- Possible mild gastrointestinal upset at high doses
- Potential skin irritation with topical contact in sensitive individuals
Contraindications
- Individuals taking warfarin or other vitamin K–dependent anticoagulants (watercress is high in vitamin K)
- Known allergy to Brassicaceae family plants
- Pregnant or nursing individuals should use cautiously due to limited safety data
Evidence notes
Limited clinical evidence specific to watercress extract. Most research uses whole watercress consumption showing modest benefits for oxidative stress and inflammation. Extract form lacks robust RCT data. Traditional use is well-established but modern extract research is preliminary.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
Related in Herbal Extract
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerMedical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.