Vitamin
Thiamin (Vitamin B1)
Also known as: Thiamine, Thiamine Mononitrate, Vitamin B1
Thiamin is an essential B vitamin required for carbohydrate metabolism, nerve function, and energy production. It plays a critical role in converting glucose into usable cellular energy.
Primary uses
- Energy metabolism support
- Nervous system function
- Carbohydrate metabolism
- Thiamin deficiency prevention
How it works
- Cofactor in pyruvate dehydrogenase complex for energy metabolism
- Essential for transketolase in pentose phosphate pathway
- Required for myelin formation in nervous system
Dosage
- Typical range
- 1.1–1.2 mg daily (RDA for adults)
- Timing
- With meals preferred
- With food
- May be taken with or without food; absorption enhanced with food
- Duration
- Daily supplementation for chronic support; therapeutic doses may vary
- Special populations
- Pregnant/lactating women: 1.4 mg daily; higher doses used therapeutically for Wernicke-Korsakoff syndrome
Forms
- Thiamine Mononitrate· 70/100
- Thiamine Hydrochloride· 70/100
- Thiamine Pyrophosphate· 70/100
Safety
Common side effects
- Very rare; occasional skin reactions at high doses
Contraindications
- None at nutritional doses; use cautiously in those with known thiamin allergy
Evidence notes
Thiamin is an essential micronutrient with extensive clinical evidence supporting its role in metabolism and neurological function. Deficiency prevention and treatment are well-established.
Grade A: Multiple well-designed human trials support the main claims.
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