Skip to main content

Phytoestrogen

Soy Isoflavones (Menopause)

Also known as: Genistein, Daidzein, Isoflavone extract, Phytoestrogens

B
Evidence

Plant estrogens from soy that may provide mild menopause symptom relief.

Primary uses

  • Hot flashes (mild)
  • Bone health
  • Cardiovascular (mild)

How it works

  • Mild estrogenic activity
  • May reduce hot flashes
  • Bone health support
  • Cardiovascular effects

Dosage

Typical range
40-80mg isoflavones daily
Timing
Divided doses
With food
Either way
Duration
Several months for effect
Special populations
Menopausal women seeking mild symptom relief

Forms

  • Isoflavone extract
  • Soy foods
  • Capsules

Safety

Common side effects

  • GI upset
  • Bloating

Contraindications

  • Hormone-sensitive cancers (controversial/discuss)
  • Soy allergy

Evidence notes

Moderate evidence for mild hot flash relief

Grade B: Some human trials support key claims; further confirmation needed.

Related in Phytoestrogen

Check a full stack

Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.

Open the checker

Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.