Phytoestrogen

Red Clover (Isoflavones)

Also known as: Trifolium pratense, Isoflavone extract, Promensil

Evidence

Isoflavone-rich herb with mild estrogenic activity for menopause symptoms.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Menopause symptoms
Bone health (mild)
Cardiovascular (mild)

How it works

Contains isoflavones (genistein, daidzein, formononetin)
Mild estrogenic activity
May reduce hot flashes
Antioxidant effects

Dosage

Typical range: 40-160mg isoflavones daily
Timing: Divided doses
With food: Either way
Duration: Several months for effect
Special populations: Menopausal women seeking mild support

Forms

Isoflavone extract
Tea/infusion
Capsules

Safety

Common side effects

Headache
Nausea
Rash (rare)

Contraindications

Hormone-sensitive cancers
Blood disorders
Surgery (stop 2 weeks before)

Evidence notes

Mixed evidence, mild effects for menopause

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

Related in Phytoestrogen

Soy Isoflavones (Menopause)B

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.