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Phytonutrient

Sulforaphane Glucosinolate (SGS)

Also known as: SGS, Glucosinolate, Sulforaphane glucosinolate, Broccoli seed extract

A
Evidence

Stable sulforaphane precursor from broccoli seeds. Powerful Nrf2 activator for detoxification and cellular protection.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Nrf2 activation
  • Detoxification
  • Cellular protection
  • Phase 2 enzyme induction

How it works

  • Converts to sulforaphane
  • Activates Nrf2 pathway
  • Induces phase 2 detox enzymes
  • Supports glutathione

Dosage

Typical range
30-100mg glucosinolate daily
Timing
With meals
With food
Yes
Duration
Safe long-term
Special populations
Detox support

Forms

  • Broccoli seed extract

Safety

Common side effects

  • GI upset

Contraindications

  • Thyroid issues (high doses)

Products containing Sulforaphane Glucosinolate (SGS)

Top-scoring supplements in our catalog that list Sulforaphane Glucosinolate (SGS) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Thorne
Hormone Advantage
90
Thorne
Broccoli Seed Extract
89
Complement
Sulfora
81
See all products →

Evidence notes

Strong evidence for Nrf2 activation and detox support

Grade A: Multiple well-designed human trials support the main claims.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.