Fatty Acid
Safflower Seed Oil Concentrate
Also known as: CLA safflower oil, conjugated linoleic acid oil, safflower oil extract, high-linoleic safflower oil
Safflower seed oil concentrate is used as a carrier and source of conjugated linoleic acid (CLA), a polyunsaturated fatty acid with preliminary evidence for body composition support. The concentrate typically provides 750-1250 mg of CLA per serving in supplement formulations.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Common questions
How much Safflower Seed Oil Concentrate should I take?
The typical range is 750-1500 mg CLA daily (from safflower oil concentrate). Consistent use for 12+ weeks typically needed to observe potential effects
When should I take Safflower Seed Oil Concentrate?
With meals to enhance absorption. Recommended with food containing fat.
Which form of Safflower Seed Oil Concentrate is best?
Softgel capsules. Other forms in the catalog: Liquid oil, Triglyceride form.
Is Safflower Seed Oil Concentrate safe?
Commonly reported: Gastrointestinal upset, Loose stools, Bloating, Nausea.
Which Safflower Seed Oil Concentrate supplement scores highest?
Nutricost CLA Softgels, at 76/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Body composition support
- CLA delivery
- Metabolic health
How it works
- CLA may modulate fat metabolism and promote fat oxidation
- Potential effects on adipose tissue regulation
- Serves as carrier oil for CLA bioavailability
Dosage
- Typical range
- 750-1500 mg CLA daily (from safflower oil concentrate)
- Timing
- With meals to enhance absorption
- With food
- Recommended with food containing fat
- Duration
- Consistent use for 12+ weeks typically needed to observe potential effects
- Special populations
- Pregnancy/lactation: limited safety data; consult healthcare provider
Forms
- Softgel capsules· 70/100
- Liquid oil· 70/100
- Triglyceride form· 70/100
Safety
Common side effects
- Gastrointestinal upset
- Loose stools
- Bloating
- Nausea
Contraindications
- Safflower allergy/sensitivity
- Bleeding disorders (theoretical risk from increased polyunsaturated fat intake)
Products containing Safflower Seed Oil Concentrate
Top-scoring supplements in our catalog that list Safflower Seed Oil Concentrate on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
CLA itself has moderate evidence from mixed clinical trials showing modest body composition benefits (typically 0.5-1.5 kg fat loss over 12 weeks). However, safflower oil as a delivery vehicle lacks robust direct clinical data; efficacy depends on CLA content and quality standardization.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
Related in Fatty Acid
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerWhere does Safflower Seed Oil Concentrate fit in your stack?
Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.
Build my stack2 questions · free · no account needed to start
Also on iPhone — get the free app
Evidence-based supplement guides, no spam
We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.
Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.