Fatty Acid
Safflower Oil
Also known as: Carthamus tinctorius oil, Safflower seed oil, High-linoleic safflower oil, Conjugated linoleic acid source
Safflower oil is a plant-based oil rich in polyunsaturated fatty acids, commonly used as a carrier for conjugated linoleic acid (CLA) in supplement formulations. Evidence for independent health benefits beyond its fatty acid content remains limited.
Primary uses
- CLA supplement carrier
- Source of linoleic acid
- Fatty acid supplementation
How it works
- Provides omega-6 polyunsaturated fatty acids (primarily linoleic acid)
- Used as delivery vehicle for fat-soluble compounds like CLA
Dosage
- Typical range
- 1,000–3,000 mg daily (as part of CLA or multi-ingredient formulas)
- Timing
- With meals
- With food
- Recommended; fat-soluble and better absorbed with dietary fat
- Duration
- Can be used long-term; no established maximum duration
- Special populations
- Generally safe in pregnancy and lactation in typical dietary amounts; those with seed allergies should use caution
Forms
- Softgel· 70/100
- Liquid oil· 70/100
- Capsule· 70/100
Safety
Common side effects
- Mild gastrointestinal upset (when used in high doses)
- Nausea
Contraindications
- Safflower allergy or sensitivity
- History of allergic reaction to Asteraceae family plants
Evidence notes
Safflower oil itself has limited independent research. Some studies suggest modest effects on inflammation or lipid metabolism, but evidence is preliminary and inconsistent. Grade reflects that it is primarily used as a carrier oil rather than an active ingredient with established benefits.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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