Bone Health
Ipriflavone
Synthetic isoflavone studied for bone density. May support bone formation and reduce breakdown.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Ipriflavone product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations '+CAL+ with Ipriflavone | 84 A- | $0.80 |
| 2 | Bluebonnet Nutrition IPRIFLAVONE 300 mg | 78 B+ | $0.55 |
| 3 | Vital Nutrients Ipriflavone 600mg | 78 B+ | $0.89 |
| 4 | Bluebonnet Nutrition SUPER BORON BONE FORMULA | 74 B+ | $0.93 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Ipriflavone should I take?
The typical range is 200mg 3x daily (600mg total). Long-term use
When should I take Ipriflavone?
With meals, divided doses. Yes.
Which form of Ipriflavone is best?
Capsules — Usually 200mg.
Is Ipriflavone safe?
Commonly reported: GI upset, Rare lymphocytopenia. Serious warnings: Monitor lymphocyte counts with long-term use. Safe
Which Ipriflavone supplement scores highest?
Pure Encapsulations '+CAL+ with Ipriflavone, at 84/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Bone density
- Osteoporosis prevention
How it works
- May inhibit bone resorption
- Supports bone formation
- Isoflavone derivative
Dosage
- Typical range
- 200mg 3x daily (600mg total)
- Timing
- With meals, divided doses
- With food
- Yes
- Duration
- Long-term use
- Special populations
- Postmenopausal, osteoporosis risk
Forms
- Capsules
Safety
Common side effects
- GI upset
- Rare lymphocytopenia
Contraindications
- Immune disorders (relative)
Products containing Ipriflavone
Top-scoring supplements in our catalog that list Ipriflavone on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Synthetic isoflavone for bones
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.