Cruciferous

Indole-3-Carbinol (I3C)

Also known as: I3C, Indole-3-carbinol, Cruciferous extract

Evidence

Cruciferous compound that converts to DIM and supports estrogen metabolism.

Primary uses

Estrogen metabolism
Hormone balance
Detoxification

How it works

Converts to DIM in stomach
Modulates estrogen metabolism
From cruciferous vegetables
Supports healthy estrogen balance

Dosage

Typical range: 200-400mg daily
Timing: With meals
With food: Yes
Duration: Ongoing for estrogen support
Special populations: Estrogen metabolism support

Forms

Capsules
With DIM

Safety

Common side effects

GI upset
Skin rash (rare)

Contraindications

Hormone-sensitive cancers (discuss)

Evidence notes

Precursor to DIM, supports estrogen metabolism

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.