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Essential Fatty Acid

Evening Primrose

Also known as: EPO, GLA source, Oenothera biennis oil, Evening Primrose Oil

C
Evidence

GLA-rich oil traditionally used for PMS, breast tenderness, and women's health.

Primary uses

  • PMS breast tenderness
  • Hormonal skin
  • Menopause (mild)
  • Hot flashes (mild)
  • Skin health
  • Breast tenderness

How it works

  • Provides GLA (gamma-linolenic acid)
  • Precursor to anti-inflammatory prostaglandins
  • Traditional for breast tenderness
  • Skin and hormone support

Dosage

Typical range
500-3000mg daily (providing 40-300mg GLA)
Timing
Divided doses with meals
With food
Yes, fat-soluble
Duration
2-3 months for PMS effects
Special populations
Women with PMS, cyclic breast tenderness

Forms

  • Softgels
  • Liquid oil

Safety

Common side effects

  • GI upset
  • Headache
  • Soft stools

Contraindications

  • Seizure disorders
  • Before surgery (blood thinning)

Evidence notes

Mixed evidence, may help PMS breast symptoms

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.