Ayurvedic

Coleus Forskohlii (Forskolin)

Also known as: Forskolin, Forskohlii, Plectranthus barbatus, Coleus Forskohlii Extract

Evidence

Coleus forskohlii is a traditional Ayurvedic plant whose root extract contains forskolin, a diterpene alkaloid that activates adenylyl cyclase and increases cAMP levels. Research suggests potential effects on body composition, metabolic rate, and cardiovascular function, though clinical evidence remains limited.

Primary uses

Thyroid stimulation
Metabolic support
Body composition
Body composition support
Metabolic rate enhancement
Cardiovascular health
Thyroid function support

How it works

Increases cAMP
May stimulate thyroid hormone release
Traditional metabolic support
Fat metabolism effects

Dosage

Typical range: 50-100mg forskolin (from 250-500mg 20% extract) 2x daily
Timing: Before meals
With food: Either way
Duration: 8-12 weeks
Special populations: Metabolic support, hypothyroid

Forms

Standardized extract
Capsules
Standardized extract (10-20% forskolin)· 70/100
Tablets· 70/100
Powders· 70/100

Safety

Common side effects

Flushing
Rapid heart rate
Low blood pressure

Contraindications

Hyperthyroidism
Low blood pressure
Heart conditions
Bleeding disorders

Evidence notes

Some evidence for thyroid and metabolism, more research needed

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

Related in Ayurvedic

GuggulC

Check a full stack

Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.

Open the checker

Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.