Ayurvedic
Guggul
Also known as: Bdellium, Commiphora mukul, Guggul (Commiphora mukul), Guggulipid
Guggul is a traditional Ayurvedic resin extract standardized to guggulsterones, studied primarily for lipid metabolism and cholesterol support. Evidence suggests modest benefits for triglycerides and cholesterol, though results are mixed and variable across studies.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Thyroid support
- Cholesterol (traditional)
- T4 to T3 conversion
- Cholesterol management
- Triglyceride reduction
- Lipid metabolism
- Cardiovascular support
How it works
- May enhance T4 to T3 conversion
- Traditional for obesity/metabolism
- Guggulsterones active compounds
- Also used for lipids
Dosage
- Typical range
- 25-50mg guggulsterones (often 500-1000mg extract) 2-3x daily
- Timing
- With meals
- With food
- Yes
- Duration
- 8-12 weeks
- Special populations
- Hypothyroid support, traditional Ayurvedic use
Forms
- Standardized extract
- Traditional resin
- Resin extract (10:1 concentration)· 70/100
- Standardized to guggulsterones (typically 2.5-5%)· 70/100
Safety
Common side effects
- GI upset
- Skin rash
- Headache
Contraindications
- Hyperthyroidism
- Liver disease
- Hormone-sensitive conditions
Evidence notes
Some evidence for thyroid and lipids, more research needed
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
Related in Ayurvedic
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.