Ayurvedic

Guggul

Also known as: Bdellium, Commiphora mukul, Guggul (Commiphora mukul), Guggulipid

Evidence

Guggul is a traditional Ayurvedic resin extract standardized to guggulsterones, studied primarily for lipid metabolism and cholesterol support. Evidence suggests modest benefits for triglycerides and cholesterol, though results are mixed and variable across studies.

Primary uses

Thyroid support
Cholesterol (traditional)
T4 to T3 conversion
Cholesterol management
Triglyceride reduction
Lipid metabolism
Cardiovascular support

How it works

May enhance T4 to T3 conversion
Traditional for obesity/metabolism
Guggulsterones active compounds
Also used for lipids

Dosage

Typical range: 25-50mg guggulsterones (often 500-1000mg extract) 2-3x daily
Timing: With meals
With food: Yes
Duration: 8-12 weeks
Special populations: Hypothyroid support, traditional Ayurvedic use

Forms

Standardized extract
Traditional resin
Resin extract (10:1 concentration)· 70/100
Standardized to guggulsterones (typically 2.5-5%)· 70/100

Safety

Common side effects

GI upset
Skin rash
Headache

Contraindications

Hyperthyroidism
Liver disease
Hormone-sensitive conditions

Evidence notes

Some evidence for thyroid and lipids, more research needed

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

Related in Ayurvedic

Coleus Forskohlii (Forskolin)C

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.