Fiber
Chitosan
Also known as: chitosan oligosaccharide, deacetylated chitin, shellfish-derived chitosan
Chitosan is a polysaccharide fiber derived from shellfish exoskeletons that has been studied for lipid management and weight support. Evidence for meaningful clinical benefit is moderate at best, with mixed results in human trials.
Primary uses
- Cholesterol support
- Weight management
- Lipid binding
How it works
- Binds dietary lipids and cholesterol in the gastrointestinal tract
- May reduce fat absorption
- Viscous fiber effects on satiety
Dosage
- Typical range
- 500–3000 mg daily
- Timing
- With meals, particularly meals containing fat
- With food
- Take with food for intended lipid-binding effect
- Duration
- Typically used as ongoing supplement; studies range 4–24 weeks
- Special populations
- Shellfish allergy is a contraindication; caution in those with seafood sensitivities
Forms
- Capsule· 70/100
- Tablet· 70/100
- Powder· 70/100
Safety
Common side effects
- Bloating
- Gas
- Mild gastrointestinal discomfort
- Constipation
Contraindications
- Shellfish allergy or sensitivity
- Severe gastrointestinal obstruction
- Caution with history of bowel obstruction
Evidence notes
Some human studies show modest effects on cholesterol and weight, but results are inconsistent and effect sizes are small. Most positive data come from older trials; more recent rigorous RCTs show limited benefit. Not strong enough for grade B.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
Related in Fiber
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerMedical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.