Weight Management

Capsaicin / Cayenne

Also known as: Capsaicin, Cayenne pepper, Capsicum

Evidence

Hot pepper compound increasing thermogenesis and reducing appetite.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Thermogenesis
Appetite suppression
Metabolism

How it works

Activates TRPV1 receptors
Increases thermogenesis
May reduce appetite

Dosage

Typical range: 30-120mg capsaicin or 500mg cayenne
Timing: With meals
With food: Yes - reduces GI irritation
Duration: Tolerance may develop
Special populations: Weight management

Forms

Capsule (coated)
Powder

Safety

Common side effects

GI burn
Sweating
Flushing

Contraindications

GI ulcers
IBS

Products containing Capsaicin / Cayenne

Top-scoring supplements in our catalog that list Capsaicin / Cayenne on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Nutricost

Cayenne Pepper Capsules

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Evidence notes

Good evidence for acute metabolic effects

Grade B: Some human trials support key claims; further confirmation needed.

Related in Weight Management

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.