Detox Support
Calcium D-Glucarate
Also known as: CDG, Calcium saccharate, D-Glucaric acid calcium salt, D-glucaric acid
Supports phase II liver detox by inhibiting beta-glucuronidase, preventing toxin and hormone reabsorption.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Calcium D-Glucarate product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | NOW Foods Calcium D-Glucarate | 81 A- | $0.33 |
| 2 | Pure Encapsulations DIM Detox | 80 A- | $1.93 |
| 3 | Pure Encapsulations Women's Pure Pack | 80 A- | $3.20 |
| 4 | NOW Foods DIM 200 | 78 B+ | $0.22 |
| 5 | Pure Encapsulations Calcium-D-Glucarate | 76 B+ | $2.47 |
| 6 | Integrative Therapeutics Calcium D-Glucarate | 72 B | $1.47 |
| 7 | Nature's Way Complete Liver Cleanse | 72 B | $1.14 |
| 8 | Natural Factors AndroSense T-Correct | 72 B | $1.00 |
| 9 | Nature's Way Protective Breast Formula | 71 B | $2.95 |
| 10 | Jarrow Formulas DIM + CDG | 65 B- | $1.00 |
| 11 | Integrative Therapeutics Detoxication Factors | 64 B- | $1.17 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Calcium D-Glucarate should I take?
The typical range is 500-1500mg daily in divided doses. Long-term use appropriate
When should I take Calcium D-Glucarate?
With meals. Either way.
Which form of Calcium D-Glucarate is best?
Capsules — Common. Other forms in the catalog: Tablets.
Is Calcium D-Glucarate safe?
Commonly reported: Rare: GI upset. Serious warnings: May increase clearance of some drugs. Safe - supports liver detox
Which Calcium D-Glucarate supplement scores highest?
NOW Foods Calcium D-Glucarate, at 81/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Hormone detox
- Estrogen clearance
- Toxin elimination
- Beta-glucuronidase inhibition
How it works
- Inhibits beta-glucuronidase enzyme
- Prevents deconjugation of toxins
- Supports estrogen excretion
- Enhances glucuronidation pathway
Dosage
- Typical range
- 500-1500mg daily in divided doses
- Timing
- With meals
- With food
- Either way
- Duration
- Long-term use appropriate
- Special populations
- Those with hormone concerns, detox support
Forms
- Capsules
- Tablets
Safety
Common side effects
- Rare: GI upset
Contraindications
- None significant
Products containing Calcium D-Glucarate
Top-scoring supplements in our catalog that list Calcium D-Glucarate on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Good mechanism understanding, some clinical evidence
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.