Immune Support
Andrographis
Also known as: Andrographis paniculata, King of Bitters, Kalmegh, Andrographis (Andrographis paniculata)
Andrographis paniculata is a traditional Ayurvedic and Southeast Asian herb containing andrographolide as its primary bioactive compound. Research suggests potential immune-supporting and anti-inflammatory properties, though evidence in humans remains moderate.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Andrographis product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Nootropics Depot Andrographis paniculata Capsules | 90 A | $0.43 |
| 2 | Nootropics Depot Andrographis paniculata Powder | 90 A | $0.40 |
| 3 | Herb Pharm Andrographis | 80 A- | $0.33 |
| 4 | Bluebonnet Nutrition WELLNESS SUPPORT | 76 B+ | $1.33 |
| 5 | Codeage Supreme Joint Health | 69 B | $1.67 |
| 6 | Gaia Herbs Sinus & Lung Supreme | 64 B- | $0.52 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Andrographis should I take?
The typical range is 200-400mg standardized extract daily. Short-term for acute illness, cycle for maintenance
When should I take Andrographis?
With meals. Yes, reduces GI upset.
Which form of Andrographis is best?
Standardized extract — 10-30% andrographolides. Other forms in the catalog: KalmCold formula, Capsules, Powder extract, Capsule, Tablet.
Is Andrographis safe?
Commonly reported: GI upset, Fatigue, Headache, Bitter taste. Serious warnings: May affect fertility, Hypotension possible. Generally safe, monitor with liver conditions
Which Andrographis supplement scores highest?
Nootropics Depot Andrographis paniculata Capsules, at 90/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Cold/flu treatment
- Sore throat
- Fever reduction
- Immune support
- Upper respiratory
- Anti-inflammatory
- Cold and flu symptom management
- Respiratory health
How it works
- Immune cell activation
- NF-kB inhibition
- Antipyretic effects
- Antiviral properties
Dosage
- Typical range
- 200-400mg standardized extract daily
- Timing
- With meals
- With food
- Yes, reduces GI upset
- Duration
- Short-term for acute illness, cycle for maintenance
- Special populations
- Acute infections, immune support
Forms
- Standardized extract
- KalmCold formula
- Capsules
- Powder extract· 70/100
- Capsule· 70/100
- Tablet· 70/100
Safety
Common side effects
- GI upset
- Fatigue
- Headache
- Bitter taste
Contraindications
- Pregnancy
- Autoimmune conditions
- Low blood pressure
Products containing Andrographis
Top-scoring supplements in our catalog that list Andrographis on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Strong clinical evidence for upper respiratory infections
Grade A: Multiple well-designed human trials support the main claims.
Related in Immune Support
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.