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Tuna
Seafood · Fatty Fish

Tuna

82Health
Score
A

Tuna is a lean, protein-dense seafood rich in omega-3 fatty acids, selenium, and B vitamins, making it a cornerstone food for cardiovascular and cognitive health.

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Why Tuna scores 82

Nutrient density35
Protein quality14
Fiber content0
Healthy fats5
Bioactive compounds11
Glycemic impact10
Top nutrients
Selenium164.7Niacin115.6Vitamin B1291.7Vitamin B654.7Phosphorus22.2

Nutrition

per_100g

130
Calories
29.2g
Protein
0g
Carbs
0.9g
Fat
0g
Fiber

Health benefits

Supports cardiovascular health and reduces atherosclerosis risk

strong evidence

EPA and DHA in tuna reduce triglycerides, lower blood pressure, and decrease platelet aggregation, while selenium acts as a cofactor for glutathione peroxidase, protecting vessel endothelium from oxidative damage

Enhances cognitive function and supports neuroprotection

strong evidence

DHA comprises ~10% of brain phospholipid membranes and modulates neuroinflammation; selenium protects against neuronal oxidative stress and supports mood regulation through antioxidant pathways

Optimizes protein synthesis and muscle retention with aging

strong evidence

Complete amino acid profile with high leucine content activates mTOR signaling; high protein density with minimal calories supports sarcopenia prevention

Reduces systemic inflammation and oxidative stress

moderate evidence

Omega-3 fatty acids suppress pro-inflammatory cytokines (TNF-α, IL-6); selenium and niacin boost endogenous antioxidant enzyme systems

Supports thyroid function and metabolic regulation

moderate evidence

Selenium is essential for thyroid peroxidase and glutathione peroxidase, protecting thyroid tissue; adequate iodine-rich seafood consumption maintains TSH homeostasis

Pairs well with

  • ·Pair with leafy greens (spinach, kale) because their vitamin K and chlorophyll enhance omega-3 absorption and amplify anti-inflammatory signaling
  • ·Combine with selenium-free carbs (sweet potato, brown rice) because resistant starch feeds beneficial gut bacteria that improve bioavailability of B vitamins
  • ·Serve with tomatoes or bell peppers because their lycopene and vitamin C reduce mercury bioavailability and boost collagen synthesis via vitamin C synergy
  • ·Add turmeric or ginger because curcumin and gingerol potentiate tuna's anti-inflammatory effects through NF-κB pathway inhibition

Practical tips

  • ·Best timing: midday
  • ·Choose skipjack or canned light tuna over albacore/yellowfin to reduce mercury exposure while maintaining omega-3 benefits; limit to 2-3 servings weekly for adults
  • ·Store fresh tuna at 32°F immediately after purchase; use within 1-2 days to prevent histamine formation (scombroid poisoning risk)
  • ·Pair canned tuna with olive oil (not water-packed) to improve omega-3 absorption via fat-soluble vitamin mechanism and enhance satiety
  • ·Consume tuna in combination with antioxidant-rich foods; this reduces oxidative stress from tuna's polyunsaturated fats during digestion
  • ·If using canned tuna, rinse with fresh water to reduce sodium content by ~40%, critical for blood pressure management in sodium-sensitive individuals

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