Primary Research · 2005
Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial
Eussen SJ, de Groot LC, Clarke R, et al. · Archives of Internal Medicine, 2005
Key finding
Dose-finding RCT in older adults found 647–1,032 µg/day oral B12 was needed to normalize mild B12 deficiency markers — orders of magnitude above the RDA, supporting high-dose oral as an alternative to injections.
About the supplement
Vitamin B12 (Cobalamin)
Dose · mechanism · evidence grade · safety →
Read the paper
Open on PubMedhttps://pubmed.ncbi.nlm.nih.gov/15883237/
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