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Stevia Extract (Stevia rebaudiana Leaf)

Also known as: Stevia rebaudiana, Stevioside, Rebaudioside A, Reb A

B
Evidence

Stevia is a non-caloric natural sweetener extracted from Stevia rebaudiana leaves, containing steviol glycosides that provide sweetness without affecting blood glucose levels. It is widely used as a sugar substitute and has been recognized as safe by major regulatory agencies.

Primary uses

  • Natural sweetening agent
  • Sugar substitute for blood sugar management
  • Low-calorie food additive
  • Weight management support

How it works

  • Steviol glycosides bind to sweet taste receptors without caloric content or metabolic impact
  • Non-fermentable by oral bacteria, reducing dental caries risk
  • May modulate glucose homeostasis through minor pharmacological effects at high doses

Dosage

Typical range
250-450 mg daily (stevia extract); as a sweetener, quantities vary by product potency and intended sweetness level
Timing
Use as needed; no specific timing requirement
With food
May be taken with or without food
Duration
Safe for long-term use; regulatory approval based on extensive safety studies
Special populations
Generally recognized as safe in pregnancy and lactation at typical dietary levels; individuals with rare genetic disorder phenylketonuria (PKU) should verify no additives in specific products

Forms

  • Powder· 70/100
  • Liquid extract· 70/100
  • Tablets· 70/100
  • Granules· 70/100

Safety

Common side effects

  • Generally well-tolerated at recommended doses
  • Rare: mild gastrointestinal effects at very high doses
  • Some individuals report aftertaste or metallic taste

Contraindications

  • No absolute contraindications at approved dietary levels
  • Theoretical concern: very high doses may have modest effects on insulin or glucose metabolism (clinically insignificant in typical use)
  • Individuals with ragweed allergy may have cross-reactivity (rare)

Evidence notes

Stevia has extensive safety data and regulatory approval from FDA, EFSA, and others. Good evidence supports its non-caloric sweetening properties and glucose neutrality in typical use. Limited clinical evidence for specific health benefits beyond sweetening; most health claims remain preliminary.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.