Herbal Extract
Trigonella foenum-graecum Extract (Fenugreek Seed)
Also known as: Fenugreek Extract, Fenugreek Seed Extract, Trigonella foenum-graecum, Methi Extract
Fenugreek seed extract contains alkaloids (trigonelline) and steroidal saponins (protodioscin) with traditional use in supporting metabolic health and hormonal balance. Evidence suggests modest benefits for blood glucose regulation and lactation support, though human clinical data remains limited.
Primary uses
- Blood glucose support
- Lactation support
- Testosterone/hormonal health
- Appetite regulation
- Cholesterol management
How it works
- Trigonelline acts as a monoamine oxidase inhibitor and may influence neurotransmitter metabolism
- Protodioscin and other saponins may modulate hormone receptor activity
- Galactomannan fiber content supports satiety and glucose modulation
- Antioxidant and anti-inflammatory effects from polyphenol compounds
Dosage
- Typical range
- 500–1,500 mg daily (standardized extract)
- Timing
- With meals to minimize GI upset
- With food
- Recommended; may reduce nausea and improve absorption
- Duration
- Safe for long-term use; most studies assess 8–12 weeks for efficacy
- Special populations
- Pregnant women should consult healthcare provider before use; generally recognized as safe for lactation support
Forms
- Capsule· 70/100
- Powder· 70/100
- Extract· 70/100
Safety
Common side effects
- Gastrointestinal upset (nausea, diarrhea, bloating)
- Maple syrup odor in urine/sweat
- Hypoglycemia in susceptible individuals when combined with antidiabetic drugs
Contraindications
- Pregnancy (traditionally avoided due to uterotonic properties)
- Allergy to legumes (fenugreek is a legume)
- Severe hypoglycemia without medical supervision
- Concurrent use with anticoagulants (theoretical risk)
Evidence notes
Fenugreek has moderate evidence for glucose control and lactation in human trials, but most research involves whole seed rather than standardized extracts. The specific 3% trigonelline / 1% protodioscin extract lacks robust RCT validation. Evidence is preliminary for hormonal claims.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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