Digestive Aid
DGL (Deglycyrrhizinated Licorice)
Also known as: Deglycyrrhizinated licorice, DGL licorice, Gut-safe licorice
Licorice with glycyrrhizin removed, safe for long-term use to soothe and protect stomach lining.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every DGL (Deglycyrrhizinated Licorice) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne GI Relief | 88 A | $0.46 |
| 2 | Pure Encapsulations Epi-Integrity powder | 85 A- | $2.00 |
| 3 | Pure Encapsulations DGL Plus | 83 A- | $0.44 |
| 4 | Pure Encapsulations G.I. Fortify | 77 B+ | $1.20 |
| 5 | Pure Encapsulations Heartburn Essentials | 75 B+ | $0.41 |
| 6 | Integrative Therapeutics EHB | 74 B+ | $1.34 |
| 7 | Integrative Therapeutics Similase Sensitive Stomach | 72 B | $0.58 |
| 8 | Integrative Therapeutics Heartburn Advantage | 68 B | $1.12 |
| 9 | Integrative Therapeutics Rhizinate | 66 B- | $0.48 |
| 10 | Nature's Way DGL | 66 B- | $0.59 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much DGL (Deglycyrrhizinated Licorice) should I take?
The typical range is 380-760mg chewed 20 minutes before meals, up to 3x daily. Long-term use safe (glycyrrhizin removed)
When should I take DGL (Deglycyrrhizinated Licorice)?
Before meals and bedtime. Before meals.
Which form of DGL (Deglycyrrhizinated Licorice) is best?
Chewable tablets — Chew before swallowing for best effect. Other forms in the catalog: Powder, Capsules.
Is DGL (Deglycyrrhizinated Licorice) safe?
Commonly reported: Rare at DGL form. Serious warnings: Ensure it's DGL, not whole licorice. Safe (glycyrrhizin removed)
Which DGL (Deglycyrrhizinated Licorice) supplement scores highest?
Thorne GI Relief, at 88/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Stomach lining
- Ulcer support
- Heartburn
- Gut soothing
How it works
- Stimulates mucus production
- Protects stomach lining
- Soothes GI tract
- Glycyrrhizin removed for safety
Dosage
- Typical range
- 380-760mg chewed 20 minutes before meals, up to 3x daily
- Timing
- Before meals and bedtime
- With food
- Before meals
- Duration
- Long-term use safe (glycyrrhizin removed)
- Special populations
- Ulcers, GERD, gastritis, H. pylori adjunct
Forms
- Chewable tablets
- Powder
- Capsules
Safety
Common side effects
- Rare at DGL form
Contraindications
- None for DGL specifically
Products containing DGL (Deglycyrrhizinated Licorice)
Top-scoring supplements in our catalog that list DGL (Deglycyrrhizinated Licorice) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Good evidence for GI mucosal support
Grade B: Some human trials support key claims; further confirmation needed.
Related in Digestive Aid
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.