Terpene

d-Limonene

Also known as: Limonene, Orange peel extract, Citrus terpene

Evidence

Citrus-derived compound that may help GERD by coating the esophagus and promoting normal peristalsis.

Primary uses

GERD support
Heartburn
Esophageal coating

How it works

Coats esophageal lining
Promotes normal peristalsis
May neutralize gastric acid
Citrus-derived

Dosage

Typical range: 1000mg every other day for 20 days, then as needed
Timing: Empty stomach
With food: Empty stomach, typically morning
Duration: Initial course then as needed
Special populations: GERD, chronic heartburn

Forms

Softgels
Orange peel extract

Safety

Common side effects

Citrus burps
GI upset

Contraindications

Citrus allergy

Evidence notes

Limited but promising research for GERD

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.