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Succinic Acid
Also known as: Succinate, Butanedioic acid
A four-carbon dicarboxylic acid and key intermediate in the citric acid cycle (Krebs cycle). Used as an energy metabolism support ingredient in wellness formulas.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Energy metabolism support
- Cellular ATP production
- Antioxidant support
How it works
- Citric acid cycle intermediate
- Electron transport chain support
- Potential anti-inflammatory effects
Dosage
- Typical range
- 250-1000 mg daily
- Timing
- With meals
- With food
- Recommended with food to minimize GI irritation
- Duration
- Limited guidance; used as part of formulas
- Special populations
- Generally recognized as safe (GRAS); limited specific data
Forms
- Capsule· 70/100
- Powder· 70/100
Safety
Common side effects
- Possible mild GI upset at high doses
Products containing Succinic Acid
Top-scoring supplements in our catalog that list Succinic Acid on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Minimal human clinical evidence; primarily mechanistic interest based on biochemical role. Very limited evidence for supplementation benefits in humans.
Grade D: Primarily pre-clinical or anecdotal; human efficacy not established.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.